Feb 17, 2025 · In addition, bempedoic acid and statin combination therapy can be used for patients sensitive to high statin doses. 6 Diagram of how bempedoic acid inhibits cholesterol synthesis within …

Jun 12, 2025 · Bempedoic Acid: A New Era in Cholesterol-Lowering Therapy Introduction For decades, statins have dominated the cholesterol-lowering landscape. While effective, they’re not always well …

Bempedoic acid provides an effective tool to further reduce LDL-cholesterol as add on therapy in patients unable to reach the target despite maximally tolerated lipid lowering therapy.

3 days ago · The inclusion of bempedoic acid reinforces its important role as a proven, evidence-based therapy for reducing both cardiovascular and limb risk in high-risk populations,” said Sheldon Koenig ...

Jun 12, 2025 · Apolipoprotein B, total cholesterol, and non-HDL-C were also reduced, particularly in the combination therapy, while hsCRP was reduced particularly in the monotherapy group with 180 mg …

Oct 15, 2023 · Bempedoic acid is a selective inhibitor of the adenosine triphosphate citrate lyase that reduces low-density lipoprotein cholesterol (LDLc) levels by 17% to 28%. Although the Evaluation of …

Bempedoic acid interferes with an enzyme in the liver that regulates cholesterol production. It allows for increased clearance of LDL-C from the blood stream leading to lower levels. Bempedoic acid is only …

Aug 26, 2024 · Introduction: Bempedoic acid is a first-in-class low-density lipoprotein cholesterol (LDL-C) lowering agent which offers an important opportunity for further LDL-C lowering in statin-intolerant ...

Jul 1, 2024 · What Does Bempedoic Acid Offer? Bempedoic acid is a prodrug that reduces rates of cholesterol and fatty acid synthesis and augments recirculation of the LDL receptor to the hepatocyte …

Feb 1, 2024 · Bempedoic acid has proven beneficial for further reduction of LDL cholesterol for targeted groups of patients. It is not only efficient but also a well tolerated, affordable, and available agent …