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  1. Drugs.com
    https://www.drugs.com › pro › digibind.html

    Digibind: Package Insert / Prescribing Information

    • Digibind is a powder of digoxin-specific Fab fragments derived from sheep antibodies. It is used to treat life-threatening digoxin or digitoxin overdose by binding and removing the toxins from the body.… See more

    Overview

    Package insert / product label
    Generic name: digoxin immune fab (ovine)

    Drugs.com
    Digibind Description

    DIGIBIND, Digoxin Immune Fab (Ovine), is a sterile lyophilized powder of antigen binding fragments (Fab) derived from specific antidigoxin antibodies raised in sheep. Production of antibodies specific for digoxin involves conjugation of digoxin as a hapten to human albumin. Sheep are immunized with this material to produce antibodies specific for the antigenic determinants of the digoxin molecule. The antibody is then papain-digested and digoxin-specific Fab fragments of the antibody are isolated and purified by affinity chromatography. These antibody fragments have a molecular weight of approximately 46,200.

    Drugs.com
    Digibind uses, antidote effects, mechanism, indications and ADR's ☠
    01:19
    Digibind uses, antidote effects, mechanism, indications and ADR's ☠
    YouTubeCentre of Learning2.5K viewsNov 8, 2017
    Digibind • LITFL • CCC Toxicology
    Digibind is a digoxin antidote that binds to digoxin and prevents its toxic effects. Learn how to use it, when to use it, and what are its adverse effects and pharmacokinetics.
    Life in the Fast Lane · https://litfl.com/digibind-…
  1. Life in the Fast Lane
    https://litfl.com › digibind-antidote

    Digibind • LITFL • CCC Toxicology

    Digibind is a digoxin antidote that binds to digoxin and prevents its toxic effects. Learn how to use it, when to use it, and what are its adverse …

  2. Wikipedia
    https://en.wikipedia.org › wiki › Digoxin_Immune_Fab

    Digoxin immune fab - Wikipedia

    Digibind is a brand name of digoxin immune fab, a product made from sheep antibodies that bind to digoxin and reverse its effects. It is used for acute or chronic digoxin poisoning, but has …

  3. DIGIFab.health
    https://digifab.health › en-us › index.html

    DIGIFab: Digoxin Immune Fab | Digoxin Toxicity Treatment | DIGIFab

    DIGIFab is a clinically proven antidote for potentially fatal digoxin toxicity. It rapidly binds and neutralizes digoxin, resolving the clinical manifestations of digoxin poisoning.

  4. Food and Drug Administration (.gov)
    https://www.fda.gov › media › download
    [PDF]

    Package Insert - DigiFab

    DIGIFAB is a digoxin immune fab (ovine) that binds and neutralizes digoxin in patients with life-threatening or potentially life-threatening digoxin toxicity or overdose. The package insert …

  5. RxList
    https://www.rxlist.com › digibind-drug.htm

    Digibind (Digoxin Immune Fab): Side Effects, Uses, …

    May 19, 2022 · Digibind is a powder of antigen binding fragments derived from sheep antibodies specific for digoxin or digitoxin. It is used to treat …

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  7. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov › books

    Digoxin Immune Fab - StatPearls - NCBI Bookshelf

    Jun 22, 2024 · Digoxin immune Fab is an antidote for digoxin toxicity, a condition typically observed in patients with atrial fibrillation and underlying heart failure. This activity focuses on …

  8. MDCalc
    https://www.mdcalc.com › calc

    DigiFab (Digibind) Dosing for Digoxin Poisoning

    Therapeutic range for serum digoxin level is 0.8–2.0 ng/mL (1.0–2.6 nmol/L). If acute poisoning and serum digoxin confirmed >10 ng/mL, give empiric …

  9. Medscape
    https://reference.medscape.com › drug

    Digibind, DigiFab (digoxin immune FAB (Antidote)) dosing, …

    Medscape - Indication-specific dosing for Digibind, DigiFab (digoxin immune FAB (Antidote)), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & …

  10. MedicinesFAQ
    https://www.medicinesfaq.com › brand › digibind

    Digibind: Uses, Dosage, Side Effects, Food Interaction & FAQ

    Jan 7, 2025 · Digibind is a prescription drug that increases the force and rate of the heartbeat and reduces the risk of heart failure. Learn about its uses, dosage, side effects, precautions, and …

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