A landmark study, titled “How error correction affects polymerase chain reaction deduplication: A survey based on unique molecular identifier datasets of short reads” recently published in ...

Rapid precision run-on sequencing (rPRO-seq) may help doctors understand disease states and treatment response in real time. Researchers at Sylvester Comprehensive Cancer Center (FL, USA) have ...

Influenza is a global health concern, due to annual epidemics of the disease and its potential to cause a pandemic with novel strain variants. Whole-genome sequencing enables ongoing surveillance and ...

Approaches incorporating rapid or digital PCR, CRISPR, syndromic testing, and multimodal systems reached new milestones this year.

Researchers in China developed a 'one-pot' Cas12i3/Cas13d-based assay, designated OBServe.v2, to discriminate between ASFV genotype I and II. This method demonstrates complete concordance with the PCR ...

DNA sequence analysis software needn't be expensive. For a decade, molecular biologist Kjeld Olesen has spent much of his spare time developing pDRAW32, a free sequence-analysis software package for ...

Meta-analysis of the predictive and prognostic value of erlotinib-related biomarkers in phase III, placebo-controlled trials in non-small cell lung cancer (NSCLC): Recommendations of the BioLOGUE ...

Molecular testing, or molecular diagnostics, refers to a group of tests that look at the genetic material in a specimen. It can detect genetic risk factors for certain diseases or provide evidence of ...

Nearly 20% of all cancers and metastases result from gene fusions—chromosomal rearrangements that lead to chimeric transcripts. This makes gene fusion detection critical for accurate diagnosis, ...