Mycobacterium tuberculosis survives in the host in antigen-presenting cells (APCs) such as macrophages and dendritic cells. APCs present antigens in association with major histocompatibility complex ...

Much effort has been spent trying to work out the origin and history of tuberculosis. Understanding these concepts could have important consequences for the development of vaccines and therapies that ...

Mtb is transmitted to the uninfected host via the aerosols propelled by the patient’s cough. The bacilli reaches the alveoli where it infects the alveolar macrophages, the first cells to get exposed ...

Pathogenic mycobacteria are able to transfer virulence factors across their complex cell wall using a type VII secretion system (T7SS)/early secreted antigenic target-6 of the kDa secretion system ...

Inhibition of growth was measured after 5 days exposure to the compound. IC 90 values show the geometric mean of at least two independent experiments to 2 s.f.. Fold change was calculated relative to ...

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Tuberculosis is a severe infectious disease that usually affects your lungs. When it spreads to your bones, it's known as skeletal tuberculosis. Tuberculosis is an airborne disease caused by a very ...

Mycobacterium tuberculosis, the bacterium responsible for tuberculosis, produces pairs of poison-antidote, called ...

Researchers suggest targeting the fatty coat of tuberculosis bacteria could enhance the effectiveness of existing TB antibiotics.

Transposon sequencing analyses reveal that among genomically diverse clinical Mycobacterium intracellulare strains and the type strain, 131 genes were comprehensively identified as universal essential ...

Researchers at Martin Luther University Halle-Wittenberg (MLU) have developed a promising new substance for targeting ...