Master the principles of MS/MS in proteomics to improve peptide sequencing accuracy. This guide covers fragmentation methods, ...

Sensitivity is a fundamental performance characteristic of a mass spectrometer. Increasingly higher sensitivities are in constant demand in order to characterize and quantify analytes that are at an ...

An algorithm designed by researchers from Carnegie Mellon University's Computational Biology Department and St. Petersburg State University in Russia could help scientists identify unknown molecules.

Thermo Fisher Scientific Inc. has announced the launch of Mass Frontier™ 6.0, a new software package offering sophisticated features for the management, evaluation and interpretation of mass spectra.

Tandem mass spectrometry is a powerful tool in proteomics. By ionizing peptides and then fragmenting those ions into smaller product ions, researchers can determine the biomolecules’ amino acid ...

For decades, mass spectrometry has been the gold standard in proteomics because of its combination of specificity, sensitivity, high target plex, and lack of requirement for affinity reagents. Yet, ...

Methylation (namely addition of a methyl group) of arginine amino acid residues of proteins is a post-translational modification (PTM) catalyzed by a family of nine enzymes called Protein Arginine ...

De novo sequencing is a method to analyze and identify peptide sequences and some post-translational modified proteins. Different from some other analysis methods, which depend on a known protein ...

For glycopeptide characterization, mass spectrometry has arisen as the go-to methodology. As well as the instrumental arrangement, a suitable software solution is essential to enable glycopeptide ...

Chemical cross-linking mass spectrometry (CXMS) is an important tool for resolving protein structures and studying protein interactions. The technique uses a chemical cross-linking agent to link two ...