The principal novel finding of this study is that lifelong low levels of HDL cholesterol due to genetic variation in HDL cholesterol–related genes are not associated with the increased risk of type 2 ...

Associations of serum lipids with cholelithiasis from Mendelian randomization. (A) Causal effects of genetically−lowered lipids on cholelithiasis. (B) Results of multivariable Mendelian randomization ...

Obesity related to metabolic syndrome was found to have a causal relationship with colorectal cancer (CRC), although this causal relationship did not exist in the opposite direction. A study published ...

Data included more than a million participants to find that Alzheimer's risk was up to 76% lower in these cases.

The instrument variable assumptions imply that all trains leaving the departure station (genetic variant) and arriving at the destination (outcome) must pass through the exposure station. They can ...

California: A study published in the journal Gut offers light on the complex relationship between serum lipids, lipid-modifying targets, and cholelithiasis, a common disease characterised by gallstone ...

In a recent study published in the JAMA Network Open, researchers performed a genetic association study using a Mendelian Randomization (MR) framework to assess associations between genetically ...