We have developed this method as an alternative to direct probe/target hybridization, which when used to study mutations in exon 11 of BRCA1 7, failed to detect the presence of the 1128insA mutation.

Figure 1: (A) Schematic of a fiber-optic DNA microarray. In this illustration microspheres functionalized with DNA sensing chemistry are randomly distributed on an optical imaging fiber surface. As ...

As mice are a vital model organism and DNA methylation is commonly used in epigenetic studies, researchers have developed a high-throughput genomic array for DNA methylation for a more detailed view ...

Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated proteins constitute a recently identified prokaryotic defense system against invading nucleic acids. DNA ...

GRAND RAPIDS, Mich. (July 13, 2022) — A new high-throughput genomic array offers an unprecedented look into the mouse epigenome, giving researchers an in-depth view into the basis of health and ...

Microarrays are a two-dimensional arrangement of biological samples, with samples placed in spots numbering in the thousands and organized into columns and rows. They allow for efficient analysis of ...

Massively parallel DNA sequencing technologies are of pivotal importance in genome biology and medicine, as they can potentially enable comprehensive and systematic evaluation of genetic variation.